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・ Alpha-lytic endopeptidase
・ Alpha-Mannosidase
・ Alpha-mannosidosis
・ Alpha-Melanocyte-stimulating hormone
・ Alpha-methylacyl-CoA racemase
・ Alpha-Methyldopamine
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・ Alpha-muurolene synthase
・ Alpha-N,N-Trimethyltryptamine
・ Alpha-N-acetylgalactosaminidase
・ Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase
・ Alpha-N-acetylglucosaminidase
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase
・ Alpha-N-arabinofuranosidase
・ Alpha-Naphthoflavone
・ Alpha-Naphthylthiourea
・ Alpha-neoagaro-oligosaccharide hydrolase
・ Alpha-Neoendorphin
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・ Alpha-Phenylcinnamic acid
・ Alpha-Pinene
・ Alpha-pinene monooxygenase
・ Alpha-pinene-oxide decyclase


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Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase : ウィキペディア英語版
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase

In enzymology, an alpha-N-acetylneuraminate alpha-2,8-sialyltransferase () is an enzyme that catalyzes the chemical reaction
:CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R \rightleftharpoons CMP + alpha-N-acetylneuraminyl-2,8-alpha-N-acetylneuraminyl-2,3-beta-D- galactosyl-R
Thus, the two substrates of this enzyme are CMP-N-acetylneuraminate and alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R, whereas its 3 products are CMP, alpha-N-acetylneuraminyl-2,8-alpha-N-acetylneuraminyl-2,3-beta-D-, and galactosyl-R. This enzyme participates in 4 metabolic pathways: glycosphingolipid biosynthesis - neo-lactoseries, glycosphingolipid biosynthesis - globoseries, glycosphingolipid biosynthesis - ganglioseries, and glycan structures - biosynthesis 2.
This enzyme belongs to the family of transferases, specifically those glycosyltransferases that do not transfer hexosyl or pentosyl groups. The systematic name of this enzyme class is CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactos ide alpha-2,8-N-acetylneuraminyltransferase. Other names in common use include cytidine monophosphoacetylneuraminate-ganglioside GM3, alpha-2,8-sialyltransferase, ganglioside GD3 synthase, ganglioside GD3 synthetase sialyltransferase, CMP-NeuAc:LM1(alpha2-8) sialyltranferase, GD3 synthase, and SAT-2.
==References==

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抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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